Humana | 2010 | 1607618532 | PDF | 415 pages | 20.3 MB
Through great experimental difficulty, we’ve witnessed rapid, crucial
developments at the intersection of computational biology, experimental
technology, and statistics through which the vital process of
transcriptional regulation can be further examined. In Computational
Biology of Transcription Factor Binding, experts in the field examine
the basic principles and pre detailed guidance for the computational
analyses and biological interpretations of transcription factor binding,
while disclosing critical practical information and caveats that are
missing from many research s. The volume serves not only computational
biologists but experimentalists as well, who may want to better
understand how to design and execute experiments and to communicate more
effectively with computational biologists, computer scientists, and
statisticians. Written for the highly successful Methods in Molecular
Biology™ series, this work pres the kind of detailed description and
implementation advice that is crucial for getting optimal results in the
lab. Authoritative and easy to use, Computational Biology of
Transcription Factor Binding guides scientists working in this area and
demands not only new experiments but also the re-annotation of existing
experimental data and computational predictions leading to important
ongoing, major paradigm changes for us all. methods in molecular
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